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background and overview[1] (3r,4s)-3-hydroxy-4-phenyl-2-azetidinone, referred to as (-)β-lactam, is a very potential chiral drug intermediate. there a…
background and overview[1] 2,4-diphenyl-oxazacyclo-5-acid is a pharmaceutical intermediate that can be prepared in two steps from (2r,3s)-3-phenylisos…
background and overview[1] (4s,5r)-2-(4-methoxyphenyl)-4-phenyl-3,5-oxazolidinedicarboxylic acid 3-tert-butyl ester is a pharmaceutical intermediate, …
background and overview p-toluenesulfonic acid (tsoh) was first prepared by jaworsky in 1865 by sulfonating toluene with sulfuric acid. in 1869, engel…
background and overview[1] 2-bromo-5-methoxyphenylboronic acid pinacol ester is a pharmaceutical intermediate commonly used in suzuki reactions. it ha…
background and overview[1-2] 2-bromo-1-chloro-4-trifluoromethoxybenzene is a pharmaceutical intermediate, which can be prepared from 2-bromo-4-(triflu…
background and overview[1-2] 3-amino-4-chlorobenzonitrile is a pharmaceutical intermediate. it can be nitrated from p-chlorobenzonitrile to obtain 4-c…
background and overview[1] 2-bromo-5-methoxyphenylboronic acid can be used as a pharmaceutical synthesis intermediate and can be prepared from 3-metho…
background and overview[1] ethyl 3-nitrophenylacetate can be used as a pharmaceutical synthesis intermediate. it can be prepared by the esterification…
background and overview[1] 1-bromo-3-fluoro-5-pyrrolidine benzene is a pharmaceutical intermediate, which can be prepared by nucleophilic substitution…
background and overview[1] ethyl 4-boron-3-chlorobenzoate can be used as a pharmaceutical synthesis intermediate and applied in suzuki coupling reacti…
background and overview[1] 4,4’-bis(2-bromoacetyl)biphenyl is a key intermediate in the synthesis of the anti-hepatitis c drug daclatasvir. daclatasvi…