Preparation and application of methyltrioctylammonium chloride_industrial additives

Background and overview^[1]

Methyl trioctyl ammonium chloride, also called trioctyl methyl ammonium chloride, is a halogenated quaternary ammonium salt. Quaternary ammonium salts are a type of cationic surfactants, among which halogenated quaternary ammonium salts (R₁R₂R₃R₄N⁺X^–) series compounds are widely used in daily chemicals, textiles, printing and dyeing, mining, asphalt, construction, plastic processing, oil mining, and petrochemical industries. and played an important role in various fields.

Preparation^[1]

Weigh 1000g trioctylamine into a beaker, add concentrated hydrochloric acid dropwise (the total amount of HCl added is about 103g), stir magnetically, after the neutralization reaction is completed, use a constant temperature water bath to evaporate to remove about 80% of the water, and then vacuum dry The product trioctyl ammonium chloride is obtained; 1000g trioctyl ammonium chloride and 235g dimethyl carbonate are respectively weighed and added to the 10L reaction kettle in turn. After purging the air in the kettle with nitrogen, the reaction is carried out in an airtight seal. The temperature is 170°C. After the reaction temperature reaches 170°C, stirring is started, and the reaction time is 8 hours; after the reaction is completed, about 1026g of methyltrioctylammonium chloride is obtained.

Apply^[2-4]

Application 1,

CN201510556325.2 discloses a preparation method of chloroisopentene. The invention uses ionic liquid as a catalyst, and the reaction steps include: using cuprous chloride and methyltrioctylammonium chloride to prepare the ionic liquid catalyst, sequentially adding isoprene and the catalyst to the reaction vessel and stirring, and then Add industrial hydrochloric acid at low temperature, then introduce hydrogen chloride gas and take samples for gas chromatography analysis during the ventilation process. Finally, the product is left to stand and separated into layers, and the chlorinated isopentene and catalyst-containing hydrochloric acid layers are recovered respectively. The new catalyst prepared by the invention can achieve an isoprene conversion rate of ≥99.0%; both the hydrochloric acid raw material and the catalyst used can be recycled; the prepared chlorinated isopentene product has high purity, low impurity content, and high molar yield. , achieved good economic benefits; the preparation method is safe, environmentally friendly, suitable for industrial production, and has broad application prospects.

Application 2,

CN201910658320.9 discloses a hydrophobic deep eutectic solvent based on paraben ester compounds, its preparation method and selective extraction application, and belongs to the technical field of heavy metal extraction, separation and enrichment. The key points of the technical solution of the present invention are: the hydrophobic deep eutectic solvent based on paraben esters uses methyl trioctyl ammonium chloride as the hydrogen bond acceptor, and uses paraben esters of different carbon chain lengths. The compound is a hydrogen bond donor and is synthesized at a molar ratio of 1:0.25~4. The invention also specifically discloses the preparation method of the hydrophobic deep eutectic solvent based on paraben compounds and its use in Cr(VI)-containing aqueous solutions from ultra-trace 0.51 μg/L to high concentration 1g/L Cr(VI). ) Application in selective extraction. The hydrophobic deep eutectic solvent prepared by the invention is used as an extraction agent and has the advantages of low cost, simple synthesis method, stable performance, low toxicity and high extraction efficiency.

Application 3.

CN201210038614. 40 kg. After stirring for 15 minutes, cool down to room temperature with cooling water and keep for 10 minutes. Then add 600 liters of n-hexane and 57 kg of benzyl chloride. Open the inlet cover and add methyltrioctylammonium chloride and raise the temperature to 62-63°C. Reflux for 8-9 hours, use cooling water to cool down to normal temperature, filter and spin dry, weigh and send to the drying room, dry at a temperature controlled between 75-80°C for 8 hours, and obtain crude adervoline. The invention uses a phase transfer catalyst, methyl trioctyl ammonium chloride, and under the catalytic action of methyl trioctyl ammonium chloride, adenine reacts with benzyl chloride to generate adevoline. The beneficial effects of the invention are that it simplifies the synthesis steps, saves a lot of energy consumption, and at the same time improves the yield and the purity of the finished product.

References

[1] [China invention, China invention authorization] CN200710008626.7 New process for the synthesis of quaternary ammonium salts

[2] CN201210038614.X A kind of synthesis method of anti-coccidial drug aderfuran

[3]CN201510556325.2 A preparation method of chlorinated isopentene

[4] CN201910658320.9 Hydrophobic deep eutectic solvent based on paraben ester compounds and its preparation method and selective extraction application